Bio-Hazard Battle is a 2d bioarcade.

An army of biogenetic mutants has gone haywire, terrorizing the world and putting the future of the planet in jeopardy. In Bio-Hazard Battle, it's up to you to take on the mutant menace and restore order and harmony to the planet Avaron, before it's too late! Through eight levels of intense action, you'll be up against some of the nastiest, most vile creatures you've ever seen, things like mega amoebas, nuclear crabs, electroworms, and gut-grabbing insects. You have four different Bioship fightercraft to choose from, each with unique handling capabilities and weapons systems. Your mission will take you through cavernous mineshafts, the ocean floor, and the Biowar Lab, each populated by heinous creatures that only man could've created. Hop into your fightercraft and save Avaron from certain doom in Bio-Hazard Battle.

The civilization on the planet Avaron is by far more advanced than that of the Earth. People developed special biogenetical creatures – giant flies, crabs, and other animals. Unfortunately, those monsters rebelled against the Avaronians and threatened to conquer the planet. It is up to you to save the planet Avaron from the invasion!

Bio-Hazard Battle is a horizontally scrolling space shooter. You can choose one of the four ships, each one having its own attacks. During the game, you can upgrade your ships' weapons by collecting colored balls floating around. You can store up to three different weapons at the same time, executing attacks in different directions.

You see, that fine planet apparently had a civilization even more advanced than Earth's, but things got a wee bit messed up. Messed up as in the planet was taken over by genetically superior species of insects, fish and other slithering creatures that go bump in the night. Fortunately, due to their high degree of technology, the Avaronians were able to regroup and mount a counterattack. With only a handful of potential fighters available, it's not a large counterattack, but it's a counterattack nonetheless. And thus begins an eight-stage shooter that will impress you at times and challenge you with regularity.

In Bio-Hazard Battle, players get to pick from four spaceships, all with a different appearance and different combination of possible special weapons they can utilize. Well, to be truthful, the ships don't actually get to use these weapons — all they're equipped to do is fire regular and charged shots straight ahead. Fortunately, each ship comes (free of charge) with a little helper-buddy pod. While this device starts out only able to shoot a couple of bullets in whatever direction it happens to be facing, it can get far more effective attacks. After destroying a wave or two of enemies during the first stage, which is simply your plane dropping from a large spacecraft down to Avaron's surface, you'll notice a number of colored globes. These are your power-ups. The green ones are the same for all four ships, simply doubling the firepower of your pod. Two separate attacks can be unleashed by picking up the red, yellow or blue globes. Which attack you get depends on which ship you're controlling. That yellow globe laser is wonderful against a number of the bosses, but can make you as helpless as a newborn baby during the many sections of the game where enemies are bombarding you from the back, top and/or bottom. Other weapons are wonderful against enemies attacking from those awkward angles and a couple are very useful in enclosed locations, such as a red globe attack that sends out large donut-shaped projectiles that bounce off walls.

Bio-Hazard Battle features:

• It's you against biogenetic mutants.
• Super-fast gameplay and awesome graphics.
• Four fightercraft to choose from.
• Eight levels of intense action.
• Use your unique weapons systems to destroy the enemy.

Bio-Hazard Battle is also known as Biohazard Battle.

The stages themselves are nicely designed. There are eight levels (although the first level can barely be classified as one) in which you’ll be forced to maneuver around some tricky obstructions. For example in the fourth stage gelatinous blue goo comes straight up from the ground forcing you to quickly fly over it, or in stage three a bulky black worm pops out of the vestiges of an observatory. The levels become very difficult starting with the fourth one, which explains why Sega gave you the grandiose number of nine credits. You’ll need them a lot at those later levels. Something I noticed is that unlike Thunder Force III, where you can easily beat any stage by memorizing it, Bio-Hazard Battle is almost always difficult no matter how many times you’ve played a certain stage.

The music is incredibly weird, but it fits the game perfectly. Every musical composition in the game sounds like it belongs in one of those low budget science fiction films, and they even fit the stage well. For example in the dank dark caverns there is a slow threatening tune and in the city it’s more upbeat and menacing. In addition the boss music is much like the stereotypical low budget flick music that everyone and their mother emulates when making fun of films like Godzilla vs The Sea Monster or It Came From Planet X. The sound effects are rather bland however. Your ship only spurts out tiny “bleeps” and “blips” with it’s amazing fire power. In addition barely any of the enemies actually make noises.

Visually, Bio-Hazard Battle is very well done, with many large and detailed enemies combined with some beautiful backgrounds. The jungle stage is a work of beauty in itself, with a few wonderfully animated insect-like enemies combined with a lush, green background that includes a number of gigantic bean pods – the product of biotechnological research gone haywire. In another example, what would be a generic battle against a gigantic plane on the sixth level is spruced up by nice graphical touches. After blowing away sections of the plane, you see tentacle-like growths protruding from the other parts of it – making it obvious that nothing on Avaron was spared from the organic onslaught.